Mir-92-o77

MirGeneDB ID

Cin-Mir-92-o77

Family name

MIR-92 (all species)

Seed

AUUGCAC

Species

Sea Squirt (Ciona intestinalis)

MiRBase ID

cin-mir-4009a

Paralogues

Cin-Mir-92-o69 Cin-Mir-92-o70 Cin-Mir-92-o71 Cin-Mir-92-o72 Cin-Mir-92-o73 Cin-Mir-92-o74 Cin-Mir-92-o75 Cin-Mir-92-o76 Cin-Mir-92-o78

Orthologues

Asu-Mir-92 Cel-Mir-92 Esc-Mir-92 Isc-Mir-92 Obi-Mir-92 Sme-Mir-92

Node of Origin (locus)

C. intestinalis

Node of Origin (family)

Bilateria

Genome context
(ci3)

HT000037.1: 4978-5031 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-92-o77)

Mir-92-o78 HT000037.1: 4884-4935 [-] UCSC Ensembl
Mir-92-o77 HT000037.1: 4978-5031 [-] UCSC Ensembl
Mir-92-o76 HT000037.1: 5092-5146 [-] UCSC Ensembl
Mir-92-o75 HT000037.1: 5191-5250 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AAUGUUCUUUCAAAAUUCACUCAUACUGAUGGUUUUCCAUGUGUAAGAGCUAUUAUGCUAUGCUAUUGCACAUGUUGUACCAACCAGUGUGUAGAUAACUCCCAUCUAAACACG

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Structure

        10         20          30        40        50      
AAUGUUCUUUCAAAAUUCA-  -       A-|   UUUC         G   UAUUA 
                    CU CAUACUG  UGGU    CAUGUGUAA AGC     \
                    GA GUGUGAC  ACCA    GUACACGUU UCG     U
GCACAAAUCUACCCUCAAUA  U       CA^   UGUU         A   UAUCG 
  110       100        90        80        70        60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-92 genes were present in the last common ancestor of bilaterians and how the vertebrate Mir-92s relate to the invertebrate Mir-92s and thus these multiple paralogues in invertebrates are classified here as orphans pending new data.

3' NTU

Motifs

Tissue expression

Cr	Cr	Cr	Cr	Cr	Cr	Cr	Cr	Cr	Cr	Ga	La	La

Star sequence

Cin-Mir-92-o77_5p*

mirBase accession

MIMAT0016501

Sequence

0- GGUUUUCCAUGUGUAAGAGC -20

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Mature sequence

Cin-Mir-92-o77_3p

mirBase accession

MIMAT0016502

Sequence

33- UAUUGCACAUGUUGUACCAAC -54

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