MirGeneDB 2.1

MirGeneDB ID

Mmu-Let-7-P2c1

Family name LET-7 (all species)
Seed GAGGUAG
Species House mouse (Mus musculus)
MiRBase ID mmu-let-7d
Paralogues Mmu-Let-7-P1b  Mmu-Let-7-P1c  Mmu-Let-7-P1d  Mmu-Let-7-P2a1  Mmu-Let-7-P2a2  Mmu-Let-7-P2a3  Mmu-Let-7-P2b1  Mmu-Let-7-P2b2  Mmu-Let-7-P2b3  Mmu-Let-7-P2c2  Mmu-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P2c1  Ami-Let-7-P2c1  Bge-Let-7  Bpl-Let-7  Bta-Let-7-P2c1  Cfa-Let-7-P2c1  Cgi-Let-7  Cli-Let-7-P2c1  Cmi-Let-7-P2c1  Cpi-Let-7-P2c1  Cpo-Let-7-P2c1  Cte-Let-7  Dan-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dno-Let-7-P2c1  Dpu-Let-7  Dsi-Let-7  Dya-Let-7  Esc-Let-7  Ete-Let-7-P2c1  Gga-Let-7-P2c1  Gja-Let-7-P2c1  Hme-Let-7  Hsa-Let-7-P2c1  Isc-Let-7  Lan-Let-7  Lch-Let-7-P2c1  Lgi-Let-7  Loc-Let-7-P2c1  Mdo-Let-7-P2c1  Mml-Let-7-P2c1  Mun-Let-7-P2c1  Npo-Let-7  Oan-Let-7-P2c1  Obi-Let-7  Ocu-Let-7-P2c1  Ovu-Let-7  Pbv-Let-7-P2c1  Pfl-Let-7  Pmi-Let-7  Rno-Let-7-P2c1  Sha-Let-7-P2c1  Sko-Let-7  Spt-Let-7-P2c1  Spu-Let-7  Sto-Let-7-P2c1  Tca-Let-7  Tgu-Let-7-P2c1  Xbo-Let-7 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(mm10)
chr13: 48536025-48536099 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P2c1)
Let-7-P2c1 chr13: 48536025-48536099 [-] UCSC Ensembl
Let-7-P2b1 chr13: 48537834-48537910 [-] UCSC Ensembl
Let-7-P2a1 chr13: 48538189-48538260 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
GACCAGCAAGAAUAAAAUGGGUUCCUAGGAAGAGGUAGUAGGUUGCAUAGUUUUAGGGCAGAGAUUUUGCCCACAAGGAGUUAACUAUACGACCUGCUGCCUUUCUUAGGGCCUUAUUAUACCAGCAUACGUUUC
Get precursor sequence
Structure
        10          20        30        40        50        60       
GACCAGCAAGAAUAAAA--|   UU       A              C      UUAGGGCAGAGAUU 
                   UGGG  CCUAGGA GAGGUAGUAGGUUG AUAGUU              U
                   AUUC  GGAUUCU UUCCGUCGUCCAGC UAUCAA              U
CUUUGCAUACGACCAUAUU^   CG       -              A      UUGAGGAACACCCG 
   130       120       110        100        90        80        70
Deep sequencing
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CommentThis is a Group 2 in human according to Kim et al (2017) but because there is a templated 3' U it is not possible according to read data to classify it as such in other taxa although the secondary structure is consistent with this categorization.
3' NTU Yes
MotifsCNNC at 3p(+17)
Tissue expression
 +
Bo Br Br Ce Em Em He In Ki Li Lu Mu Ov Pa Sk Sp Sp Te
Mature sequence

Mmu-Let-7-P2c1_5p

mirBase accessionMIMAT0000383
Sequence
0- AGAGGUAGUAGGUUGCAUAGUU -22
Get sequence
Proposed targets microrna.org: MIMAT0000383
TargetScanVert: mmu-let-7d-5p
miRDB: MIMAT0000383
Star sequence

Mmu-Let-7-P2c1_3p*

mirBase accessionMIMAT0000384
Sequence
54- CUAUACGACCUGCUGCCUUUC -75
Get sequence
Proposed targets microrna.org: MIMAT0000384
TargetScanVert: mmu-let-7d-3p
miRDB: MIMAT0000384